Description: OcuTone 90c is available by Douglas Laboratories.
amni® original formula
A Dietary Supplement
90 Vegetarian Capsules
by Douglas Laboratories®, is a dietary supplement providing a
well-balanced spectrum of key nutrients that are important in
maintaining normal eye function. OcuTone delivers generous amounts of
lutein, beta-carotene, flavonoids, glutathione, sulfurcontaining amino
acids, trace elements and a comprehensive array of antioxidant
OcuTone may be taken as a dietary
supplement to increase intake of selected nutrients that have special
importance for normal eye function.
More than any other tissue in the body,
the ocular lens and retina are continually exposed to oxygen and
intense light radiation. Both light and oxygen can create free radicals
that play havoc with lipids in the membranes of visual cells. Experts
believe that the uncontrolled generation of free radicals in the eyes
can ultimately lead to macular degeneration and cataracts. Therefore,
ocular tissues rely on a strong antioxidant defense system to protect
them from free radical damage. OcuTone was formulated to provide a
comprehensive combination of antioxidant nutrients that research has
found to be important for proper eye nutrition.
includes nutritionally meaningful amounts of lutein, betacarotene,
antioxidant vitamins, the trace elements zinc and selenium, the
cellular antioxidants glutathione and N-Acetyl-L-Cysteine, the amino
acid taurine, and potent flavonoids from bilberries and grape seeds.
Lutein. Lutein is a carotenoid similar to beta-carotene. Recent
research has shown that lutein is the major eye pigment of the outer
retina. Lutein is especially concentrated in the rods, which are the
visual cells of the retina that are responsible for black and white
vision in the dark. The rods contain complex membranes rich in
polyunsaturated fatty acids that are especially susceptible to lipid
peroxidation and free radical damage. Lutein is a potent antioxidant,
and researchers believe that the rods require it to protect themselves
from light-induced freeradical damage.
Lutein occurs naturally
in the diet, especially in dark green leafy vegetables, broccoli and
kale. Most people derive about 1 to 2 mg of lutein daily from their
diets. Epidemiological studies have shown that daily lutein intakes of
5 to 15 mg may be more appropriate for maintaining normal eye function
during aging. As a result, OcuTone was formulated to provide 15 mg of
natural lutein complex daily in three capsules. Beta-Carotene.
Beta-Carotene serves at least two purposes for the eyes. It is a
valuable precursor for vitamin A which functions in the rod cells as a
light receptor. Beta-Carotene is also an important antioxidant in the
lens and retina. OcuTone delivers 12 mg of betacarotene daily to ensure
a reliable supply of this important eye nutrient. Vitamins C and E.
healthy ocular lens is rich in the antioxidant vitamins C and E, which
scavenge oxygenand light-induced free radicals. In the lens, excessive
free radicals can lead to protein oxidation and polymerization,
resulting in opaque, cloudy precipitates. High levels of vitamins C and
E, and other natural antioxidant defense systems appear to be necessary
for complete protection of the delicate, highly transparent lens
proteins. OcuTone provides 500 mg of vitamin C and 400 I.U. of natural
vitamin E as d-alpha-tocopherol succinate. Zinc. Zinc is essential for
normal visual signal transduction in the retina. Zinc is part of many
of the enzymes involved in vitamin A-dependent light reactions in the
Moreover, zinc is an essential cofactor of
superoxide dismutase, an antioxidant enzyme that removes potentially
dangerous superoxide radicals in the visual cells, the lens, and other
tissues. OcuTone provides 6 mg of zinc in the highly bioavailable
monomethionine form. Selenium. Selenium is the essential cofactor of
the antioxidant enzyme glutathione peroxidase, which is abundant in
healthy eyes. Glutathione peroxidase levels, however, decline with
advancing age, and experts believe that adequate selenium nutrition can
help maintain normal production of this important enzyme. OcuTone
provides 50 mcg of Selenium, which is roughly equivalent to the
required daily amount. Glutathione and N-Acetyl-L-Cysteine. Glutathione
is the essential cosubstrate for glutathione peroxidase.
carry out its antioxidant functions, this enzyme requires a steady
supply of glutathione. In addition, glutathione by itself protects the
proteins in the lens from becoming insoluble and cloudy. Although well
absorbed, dietary Douglas Product Data Laboratories® (continued on
reverse) glutathione can not enter the cell, and exerts much of its
beneficial antioxidant effects in the extracellular space. NAcetyl-
L-Cysteine (NAC) easily enters the cell and is used to synthesize
intracellular glutathione. NAC also appears to have antioxidant
properties by itself. Many studies have shown that ocular glutathione
levels decline as we age. Dietary supplementation with both glutathione
and NAC may help maintain normal extracellular and intracellular
Therefore, OcuTone combines a significant
50 mg of glutathione with 300 mg of NAC. Taurine. Taurine, a
conditionally-essential sulfur amino acid, is the most abundant free
amino acid in ocular tissues, where it may function as a membrane
stabilizer, antioxidant, osmotic regulator, and neurotransmitter.
Taurine is important in maintaining normal extra- and intracellular
distribution of calcium. This in turn has implications forn euronal
excitability and the regulation of osmotic pressure. OcuTone provides
300 mg of pure taurine. Bilberry Extract. Bilberries (Vaccinium
myrtillus), a northern European cousin of North American blueberries,
are a rich source of anthocyanosides, a class of flavonoids recognized
for their importance in eye health. Bilberry anthocyanosides are potent
antioxidants in the visual cells of the retina, and help maintain
normal blood flow in the fine capillary blood vessels that nourish the
eyes and other tissues.
Three capsules of OcuTone contain 60
mg of a standardized 25 % anthocyanoside extract made from ripe Swedish
bilberries. Grape Seed Extract. Grape seed extract is rich in
proanthocyanidins, another group of important flavonoids.
Proanthocyanidins are highly regarded for their strong antioxidant
properties and their role in supporting the body’s capillary blood
vessel system. Three capsules of OcuTone provide 50 mg of highquality
European grape seed extract (from Vitis vinifera) with a minimum of 92
Serving Size: 3 vegetarian capsules
Servings Per Container: 30
Amount Per Serving
Vitamin A ...10,000 IU
(100% as natural beta-carotene from D. salina)
Vitamin C ...500mg
(as L-ascorbic acid)
Vitamin E ...400 IU
(as d-alpha tocopheryl succinate)
(as zinc monomethione**)
(as selenium amino acid complex)
N-Acetyl-L-Cysteine USP ...300mg*
(as L-glutathione, reduced)
Bilberry Fruit, dried extract, ...60mg*
min. 25% anthocyanosides
Grape Seed, dried extract, ...50mg*
min. 92% proanthocyanidins
* Daily Value not established
** OptiZinc™ brand of methionine-bound zinc is a trademark of InterHealth Company.
Cellulose, Vegetable Stearate, Silica
As a dietary supplement, adults take 3 capsules daily with food or as directed by your healthcare professional.
KEEP OUT OF REACH OF CHILDREN.
For optimal storage conditions, store in a cool, dry place.
Tamper resistant package, do not use if outer seal is missing.
(35-65% relative humidity)
These statements have not been evaluated by the Food and Drug
Administration. These products are not intended to diagnose, treat
cure, or prevent any diseases.