Description: Lipoic Acid 100mg 60 is available by Douglas Laboratories.
(as alpha-Lipoic Acid)
A Dietary Supplement
Alpha-Lipoic Acid capsules, provided by Douglas Laboratories, contain 100 mg of pure Alpha-Lipoic Acid.
Alpha-Lipoic Acid is a non-vitamin coenzyme that carries out important metabolic and antioxidant functions in the body.
Alpha-Lipoic Acid may be a beneficial dietary supplement for individuals who wish to supplement with lipoic acid.
Alpha-lipoic acid is a nutritional
coenzyme that participates in the energy metabolism of proteins,
carbohydrates and fats, with a particular role in blood glucose
disposal. It is also able to scavenge a number of free radicals. As
both a fat and water-soluble, sulfur-containing coenzyme, alpha-lipoic
acid functions in the body as part of several multi-enzyme complexes
located in the mitochondria.
Alpha-lipoic acid is essential for
metabolizing carbohydrates, proteins, and fats, for the conversion of
their energy into ATP. Two of these enzyme complexes, pyruvate
dehydrogenase (PDH) and alpha-ketoglutarate dehydrogenase (KGDH) are
part of the citric acid cycle (Krebs cycle), and as such assume a
central role for general energy production. Another lipoic acid
containing enzyme complex, branched-chain ketoacid dehydrogenase
(BCKADH), is involved in deriving energy from the branched chain amino
acids, leucine, isoleucine, and valine.
A related metabolic
function of alpha-lipoic acid is its role in blood glucose disposal.
This important coenzyme appears to be necessary for the normal
transport of blood glucose into the cell. This may be explained by its
functions in the glucose-metabolizing enzymes, PDH and alpha-KGDH, but
some researchers suspect a more direct role in cellular glucose uptake
at the cell membrane. As early as 1959, alpha-lipoic acid was suggested
to be an antioxidant, since it could extend the actions of vitamin C in
guinea pigs, and those of Vitamin E in rats.
It is only
recently, however, that the specific actions of alpha-lipoic acid in
free radical quenching, metal chelation, and antioxidant regeneration
have been investigated. Body cells and tissues are threatened
continuously by damage caused by toxic free radicals and reactive
oxygen species (e.g., peroxides) which are produced during normal
oxygen metabolism, and by toxic agents in the environment. Free
radicals, once formed, are capable of disrupting metabolic function and
cell structure. When this occurs, additional free radicals are produced
which, in turn, can result in more extensive damage to cellular
structure and function. Alpha-lipoic acid is unique among biological
antioxidants, because it is soluble in both water and lipids. This
allows it to neutralize free radicals just about everywhere in the
body, inside and outside the cells.
Due to its unique
sulfurcontaining structure, alpha-lipoic acid can scavenge several
types of free radicals, such as the highly reactive hydroxyl, and
singlet oxygen free radicals. It is also capable of suppressing the
generation of free radicals in the first place, since alpha-lipoic acid
chelates transition metals, such as iron and copper. Because
alpha-lipoic acid is involved in so many different antioxidant
functions in virtually all body tissues, it has been called the
universal antioxidant. Besides being a universal free radical
scavenger, alphalipoic acid can also recharge other antioxidant systems
throughout the body. As mentioned earlier, it can extend the activity
of Vitamins C and E. In addition, alpha-lipoic acid can also regenerate
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving
alpha-Lipoic Acid ...100mg*
* Daily Value not established
Cellulose, Gelatin (capsule), Silica, Vegetable Stearate
Does Not Contain:
Yeast, Wheat Gluten, Soy Protein, Milk/Dairy, Corn, Sodium, Sugar, Starch, Artificial Coloring, Preservatives, Flavoring
As a dietary supplement, adults take 1 capsule 1 to 2 times daily or as directed by your healthcare professional.
KEEP OUT OF REACH OF CHILDREN.
For optimal storage conditions, store in a cool, dry place.
Tamper resistant package, do not use if outer seal is missing.
(35-65% relative humidity)
These statements have not been evaluated by the Food and Drug
Administration. These products are not intended to diagnose, treat
cure, or prevent any diseases.